DEXA 2022 and its associated conferences and workshops are leading international conferences and workshops for researchers, developers, scientists, and industry practitioners to share and discuss their new ideas, original research results and practical development experiences from all Database and Expert Systems Applications (DEXA), Big Data Analytics and Knowledge Discovery (DaWaK), Electronic Government and the Information Systems Perspective (EGOVIS), Biological Knowledge Discovery from Data (BIOKDD), Cyber-Security and Functional Safety in Cyber-Physical Systems (IWCFS), Machine Learning and Knowledge Graphs (MLKgraphs), Artificial Intelligence for Clean, Affordable and Reliable Energy Supply (AI-CARES), AI System Engineering: Math, Modelling and Software (AISys), Time Ordered Data (ProTime), Applied Research, Technology Transfer and Knowledge Exchange in Software and Data Science (ARTE) and Distributed Ledgers and Related Technologies (DLRT) field.