Color tuning of visual rhodopsins: a quantitative explanation by electrostatic calculations
Sprache des Vortragstitels:
81. Jahrestagung der DPG und DPG-Frühjahrstagung
Sprache des Tagungstitel:
Rhodopsins are biological pigment-protein complexes found in photoreceptor cells of the retina. Comparing the results of two quantum chemical/electrostatic calculation methods, that have been applied successfully to reveal the functional states of BLUF photoreceptors  and photosystem II antenna protein CP29 , we have estimated absorption shifts of the retinal chromophore for a series of site-directed mutants. Our results are in excellent agreement with recent experimental studies  and strongly suggest that the spectral sensitivity in animal rhodopsins is dominated by electrostatic tuning.
 F. Collette et al., J. Phys. Chem. B 118, 11109 (2014).
 F. Müh et al., Phys. Chem. Chem. Phys. 16, 11848 (2014).
 W. Wang et al., Science 338, 1340 (2012).