P-N-Compounds as synthons in cyclisation reactions
Sprache des Vortragstitels:
8th International Phosphorus Workshop (IPW8) in Rostock (Germany)
Sprache des Tagungstitel:
Phosphorus chemistry has always been a source of unusual reactivity paired with a resulting incredible broad variety of structural motifs with different non-metallic as well as metallic elements. In recent years the chemistry of P-N-containing
synthons and derived reaction products with different unsaturated reaction partners has found increasing interest due to the interesting properties of the obtained compounds as well as the synthetic possibilities they offer. Species
containing P-N multiple bonds are highly reactive and difficult to handle.
However, the application of such precursor compounds enables the release of these reactive species by adding another reagent like a Lewis acid in solution to avoid the necessity to prepare such reactive species beforehand.
The contribution will deal with the reactivity of such in situ-prepared P-N species with different unsaturated substrates, especially alkenes, alkynes and dienes, to obtain so far unknown cyclisation products and to observe the mechanism of
such reactions by spectroscopic methods like
NMR (Nuclear Magnetic Resonance). The effect of the used additives like Lewis acids is investigated as
well as the possible preparation and application of alternative sources of P-N synthons and sophistically designed unsaturated substrates.