Krstyna Pluhackova, Andreas Horner,
"Native-like membrane models of E. coli polar lipid extract shed light on the importance of lipid composition complexity"
, in BMC Biology, 1-2021
Original Titel:
Native-like membrane models of E. coli polar lipid extract shed light on the importance of lipid composition complexity
Sprache des Titels:
Englisch
Original Kurzfassung:
Lipid-protein interactions stabilize protein oligomers, shape their structure, and modulate their function. Whereas in vitro experiments already account for the functional importance of lipids by using natural lipid extracts, in silico methods lack behind by embedding proteins in single component lipid bilayers. However, to accurately complement in vitro experiments with molecular details at very high spatio-temporal resolution, molecular dynamics simulations have to be performed in natural(-like) lipid environments.
Forschungs-