Robert Wille, Bing Li,
"Design Automation for Labs-on-Chip: A New Playground for SoC Designers"
: International System-on-Chip Conference (SOCC), 2017
Design Automation for Labs-on-Chip: A New Playground for SoC Designers
Sprache des Titels:
International System-on-Chip Conference (SOCC)
In the recent years, microfluidic technology has paved the way for so-called Labs-on-Chips (LoCs) - a convenient and cost-effective way to conduct biochemical, biological, or medical experiments. Instead of conducting tests manually in a fully equipped lab using up lab equipment and human resources, LoCs allow us to conduct biochemical and medical experiments on a small chip. This requires much smaller sample/reagent volumes and allows for a significantly higher throughput.
At the same time, designing the corresponding chips has become a considerably complex task. State-of-the-art LoCs are comprised of thousands - even tens of thousands ? of entities and a million features in order to conduct certain experiments with increasing tendency. Time to market constraints and fault tolerance considerations will further complicate the design. Despite the complexities, most of the LoCs are designed manually: Engineers draw the designs for corresponding devices by hand ? a costly and time-consuming process.
In this tutorial, we provide an overview on different LoC technologies (including electrowetting-based and flow-based LoCs as well as solutions based on two-phase microfluidics) as well as the corresponding design tasks. Afterwards, we sketch how to tackle the resulting challenges by design automation. By this, attendees of the tutorial will get introduced into a new application area where System-on-Chips play a major role to employ the respective laboratory experiments on an LoC as well as to control the biochemical actions.