Non-enzymatic glucose sensing on copper-nickel thin film alloy
Sprache des Titels:
A simple and cost efficient glucose sensor was constructed using 3D printing having as active material
a copper-15 at.% nickel thin film thermally co-evaporated on copper plated circuit boards. The glucose detection in alkaline solution was studied in detail
by cyclic voltammetric and chronoamperometric measurements. The sensor suitability for being used in both quantitative and qualitative glucose detection
was demonstrated and calibration of its response to various amounts of glucose revealed two linear regimes with different sensitivities. Glucose levels
between 0 and 10 mM are most efficiently quantified as indicated by an amperometric signal increase of 240 ?A cm?2 for each 1 mM increase of glucose concentration.
The potentiostatic stability of the sensor was evaluated and its complete insensitivity after 7 h was solely attributed to the irreversible transformation
of glucose into gluconolactone. A sensor life time of 20 cycles was demonstrated during potentiodynamic cycling when the sensor response remains constant at
its maximum level. The magnitude of possible glucose quantification errors were evaluated as interferences induced by additions of ascorbic and uric acids.
A worst case scenario of 96 % accuracy of glucose levels quantification was demonstrated using 25 times higher concentrations of interfering substances as
compared to the glucose level