Phillip Jungk, Fabian Fischer, Marko Hapke,
"In Situ-Generated Chiral Co(I)-Catalyst for Asymmetric [2+2+2] Cycloadditions of Triynes"
, in American Chemical Society, in ACS Catalysis, Vol. 6, Nummer 5, Seite(n) 3025?3029, 2016
In Situ-Generated Chiral Co(I)-Catalyst for Asymmetric [2+2+2] Cycloadditions of Triynes
Sprache des Titels:
The development of an in situ catalytic system based on cobalt(II)-salts, chiral P,N-ligands, and a reductant for the intramolecular asymmetric cyclization of triynes is described. This system represents the first chiral in situ-generated Co(I)-catalyst system for asymmetric [2+2+2] cycloadditions. The system consists only of commercially available components and leads to high yields and selectivities for the [2+2+2] cycloaddition of triynes in up to 16 examples.