Damir Posavec, Rainer Müller, Udo Bogner, Günther Bernhardt, Hrg. Günther Knör,
"Polyvinyl Butyral DMN-Conjugates for the Controlled Release of Singlet Oxygen in Medical and Antimicrobial Applications"
, in Biomaterials and Biomechanics in Bioengineering, Vol. 1, Nummer 2, Seite(n) 63-68, 2014, ISSN: 2465-9959
Original Titel:
Polyvinyl Butyral DMN-Conjugates for the Controlled Release of Singlet Oxygen in Medical and Antimicrobial Applications
Sprache des Titels:
Englisch
Original Kurzfassung:
Covalent attachment of 1,4-dimethylnaphthalene (DMN) based endoperoxide forming subunits to a polyvinyl butyral (PVB) backbone has been achieved. The functionalized polymer materials prepared and characterized here can serve as biocompatible carrier systems for studying cellular uptake, intermediate storage and delayed release of singlet oxygen, which opens up new doors for optimizing a variety of medical applications of photogenerated DMN-endoperoxides such as antiviral, antibacterial, antiplasmodial and antitumor activity.