Adetayo Kasim, Suzy Van Sanden, Martin Otava, Sepp Hochreiter, Djork-Arné Clevert, Willem Talloen, Dan Lin,
"?-Clustering of Monotone Profiles"
, in Dan Lin, Ziv Shkedy, Daniel Yekutieli, Dhammika Amaratunga, Luc Bijnens: Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R, Serie Use R!, Springer, Seite(n) 135-149, 2012, ISBN: 978-3-642-24007-2
Original Titel:
?-Clustering of Monotone Profiles
Sprache des Titels:
Englisch
Original Buchtitel:
Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R
Original Kurzfassung:
In Chaps. 7 and 8, we discussed several testing procedures to detect differentially expressed genes with monotone relationship with respect to dose. The second question of primary interest in dose-response studies is the nature (or the shape of curve) of the dose-response relationship. In the context of dose-response microarray experiments, we wish to group (or classify) genes with similar dose-response relationship. Similar to the previous chapters, the subset of genes with monotone relationship is of interest.