Andreas Mayr, Djork-Arné Clevert, Sepp Hochreiter,
"Detection of Nonlinear Effects in Gene Expression Pathways"
: ISMB 2010 Proceedings, 7-2010, Poster presentation at 18th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB), Boston, MA USA, July 11 - July 13 2010
Original Titel:
Detection of Nonlinear Effects in Gene Expression Pathways
Sprache des Titels:
Englisch
Original Buchtitel:
ISMB 2010 Proceedings
Original Kurzfassung:
Feedback loops and signal cascades lead to genetic pathways with nonlinear dependencies of their expression values. To identify genes of a pathway with nonlinear dependent expression values, we suggest a novel quadratic factor analysis algorithm. Noise and nonlinearities are distinguished by computing p-values for linear genes detected as nonlinear randomly.
Sprache der Kurzfassung:
Englisch
Erscheinungsmonat:
7
Erscheinungsjahr:
2010
Notiz zum Zitat:
Poster presentation at 18th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB), Boston, MA USA, July 11 - July 13 2010