Sparse Factor Analysis for Detecting Copy Number Variations (CNVs)
Sprache des Titels:
Englisch
Original Buchtitel:
ISMB 2009 Proceedings
Original Kurzfassung:
Most reported CNVs affect less than three HapMap samples. We model these sparse CNVs by Laplace or multimodal distributions, where learning is based on variational and EM approaches. With Affymetrix SNP6 chips on the HapMap data we found novel CNVs. Moreover many known CNVs seem to be false positives.
Sprache der Kurzfassung:
Englisch
Erscheinungsmonat:
6
Erscheinungsjahr:
2009
Notiz zum Zitat:
Poster presentation at 17th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB) & 8th European Conference on Computational Biology (ECCB), Stockholm, Sweden, June 27 - July 2 2009
Forschungs-