Joachim Zuschrader, Wolfgang Schöfberger, Heinz Falk,
"A carbohydrate-linked hypericinic photosensitizing agent"
, in Monatshefte für Chemie - Chemical Monthly, Vol. 139, Springer, Seite(n) 1387-1390, 2008, ISSN: 0026-9247
Original Titel:
A carbohydrate-linked hypericinic photosensitizing agent
Sprache des Titels:
Englisch
Englische Kurzfassung:
With respect to an enhanced solubility under physiological conditions, a carbohydrate-containing hypericin-based second-generation photosensitizer was prepared. Its photochemical properties were tested by means of the light-sensitized destruction of bilirubin IXalpha to be even better than those of the parent compound hypericin. Investigations on binding-interactions with DNA showed promising results as well.