Doktoratskolleg "Nano-Analytik von zellulären Systemen" (NanoCell)
Sprache der Bezeichnung:
Deutsch
Original Kurzfassung:
Das wissenschaftliche Ziel dieses Graduiertenkollegs ist es, Einblicke in die Dynamik und Anordnung von zellulären Molekülen und ihrer Erkennung an der Membranoberfläche zu gewinnen, sowie die Initialisierung und den Vorgang von Zellprozessen wie etwa Membrantransport, Beweglichkeit und Differenzierung zu verstehen. Funktionelle und strukturelle Untersuchungen werden sowohl an Modellen als auch an nativen Systemen vorgenommen, angefangen von einzelnen Proteinen in rekonstituierten Umgebungen bis hin zu subzellulären und zellulären Proben. Das wesentliche Ziel ist es, molekulare Expression, strukturellen Anordnungen und molekulare Erkennung, sowie Membrantransport, Zellbeweglichkeit und Differenzierung zu verstehen und zu verbinden.
Sprache der Kurzfassung:
Deutsch
Englische Bezeichnung:
Nano-Analytics of Cellular Systems
Englische Kurzfassung:
The scientific goal of this graduate program is to gain insight into the dynamics and the molecular assembly of cellular molecules, about their recognition on the membrane surface, and on the initiation and performance of cellular processes, such as membrane transport, motility, and differentiation. Functional and structural investigations are carried out on both model and native systems, from single proteins in reconstituted environments to sub-cellular and cellular samples. The major aim is to span the gap between the processes of expression, structural arrangements, and molecular recognition on one side, and membrane transport, cell motility, and differentiation on the other side. As the program focuses on frontier research in life science and cellular nano-research, it integrates numerous fields encompassing biophysics, cell biology, nanotechnology, soft matter physics, molecular and structural biology, genetics, bio-organic and inorganic chemistry, theoretical physics, mathematical modelling, and scientific computing. Novel approaches in biophysics, cellular biology and data analysis provide a solid basis for the education and the training of the students within the NanoCell program. Training next generation multidisciplinary graduates in competitive research projects is of predominant importance to the project. The students are educated in current concepts of biophysics, biochemistry, molecular and cell biology, imaging, spectroscopy, macromolecular modelling, molecular recognition and mechanics, cellular transport and motility, as well as in a range of advanced bio-analytical methodologies, nanoscopy, next generation sequencing, and data-analysis. An integrated interdisciplinary teaching program, consisting of core lectures, specialized lecture courses, laboratory courses, lab rotations, soft skills training, and international exposure at conferences and stays abroad prepare them for a successful career as scientists.